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LAKE FOREST, Ill., April 13, 2021 – Jaguar Gene Therapy, a company accelerating breakthroughs in gene therapy for patients suffering from severe genetic diseases, today announced it has closed a $139 million Series B funding co-led by Eli Lilly and Company and Deerfield Management. Also participating in the round were ARCH Venture Partners, co-founded by Robert Nelsen and one of the largest early-stage technology venture firms in the United States, Goldman Sachs, and Nolan Capital, the investment fund of former AveXis CEO and current Jaguar Executive Chairman Sean P. Nolan.
“We are thrilled to have attracted this prestigious group of visionary investors, which affirms our strategic approach, promising pipeline programs, and unique collaboration with Deerfield Management,” said Joe Nolan, Chief Executive Officer of Jaguar Gene Therapy. “With this capital infusion, we are well positioned to execute on our mission to accelerate breakthroughs in gene therapy and bring them to children and adults with severe genetic diseases.”
Led by former AveXis leadership, Jaguar leverages a proven management team with the expertise to accelerate the development, manufacturing and commercialization of novel gene therapy treatments for patients suffering from severe genetic diseases, including galactosemia, genetic causes of autism spectrum disorder, Type 1 diabetes and Bardet-Biedl syndrome.
“We are excited to engage in Jaguar Gene Therapy’s endeavor to develop novel gene therapies, following the breaking science in this rapidly advancing field,” said Andrew Adams, Ph.D., Vice President of New Therapeutic Modalities at Lilly. “With this investment, we hope Jaguar can accelerate the advancement of a diverse set of innovative medicines for patients.”
Jaguar Gene Therapy will use the proceeds of the Series B funding, together with its existing cash resources, to advance its initial pre-clinical pipeline of AAV9-based gene therapies:
Additionally, Axovia Therapeutics, a majority-owned subsidiary of Jaguar Gene Therapy that is focused on creating transformative therapies for ciliopathies, is advancing AXV101, a gene therapy treatment for BBS1, a subset of Bardet-Biedl syndrome (BBS). A life-threatening neurometabolic condition, BBS causes progressive vision loss, severe obesity, learning disorders and kidney disease.
“We are proud to invest in Jaguar Gene Therapy from our Fund XI, which was launched this year to support early-stage biotechnology companies that aim to meaningfully change medicine for the better,” said Robert Nelsen, Managing Director at ARCH Venture Partners. “Having worked closely with the Jaguar senior team members when they were leading AveXis, I have first-hand experience of their expertise, creativity, flexibility, resilience and proven track record of success in gene therapy development, manufacturing and commercialization.”
Jaguar Gene Therapy, LLC is accelerating breakthroughs in gene therapy for patients suffering from severe genetic diseases. Led by former AveXis leadership, Jaguar leverages a proven management team with the expertise to accelerate the development, manufacturing and commercialization of novel gene therapy treatments. For more information, please visit www.jaguargenetherapy.com and follow Jaguar Gene Therapy on LinkedIn.